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Home> Products > Pharmaceuticals and Biochemicals > Pharmaceutical > CAS DataBase Listed 7 > CAS 79902-63-9
79902-63-9 structure

CAS 79902-63-9 Simvastatin | Products & Prices & Suppliers

  • Simvastatin, with the chemical formula C25H38O5, has the CAS number 79902-63-9. It is a white to off-white, crystalline powder with no distinct odor. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. Its basic structure consists of a lactone ring attached to a substituted hexahydroindole ring. This compound is practically insoluble in water, but freely soluble in chloroform, methanol, and ethanol. Simvastatin is a prescription medication used to lower cholesterol and triglyceride levels in the blood. It is also used to reduce the risk of heart attack, stroke, and other cardiovascular events in individuals with high cholesterol levels. Safety information indicates that Simvastatin may cause side effects such as muscle pain, liver problems, and digestive issues. It should be used with caution in patients with liver disease or who consume large amounts of alcohol. Simvastatin should not be taken during pregnancy or while breastfeeding. It is important to consult a healthcare professional before starting or stopping Simvastatin treatment.

    Applicable Fields

    Cardiovascular Health: Simvastatin is primarily used in the field of cardiovascular health. Its purpose is to lower cholesterol and triglyceride levels in the blood, thereby reducing the risk of heart disease, heart attack, stroke, and other cardiovascular events. The mechanism of action of Simvastatin involves inhibiting the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis in the body. By inhibiting this enzyme, Simvastatin helps to decrease the production of cholesterol and increase the clearance of LDL cholesterol from the bloodstream.

    Storage

    ConditionsStore in a cool and dry place.

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  • Name: Simvastatin
  • Molecular Weight: 418.56622
  • Formula: C25H38O5
  • Synonyms: (1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste; (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate; (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate; [(1S,3R,7R,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-oxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoat; [1S-[1a,3a,7b,8b(2S*,4S*),8ab]]-2,2-Dimethylbutanoic Acid1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester; [1S-[1α,3α,7β,8β(2S^^,4S^^),8αβ]-2,2-Dimethylbutanoic acid 1,2,3,7,8,8α-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-y1)ethyl]-1-naphthyl ester;
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product Computational chemical data

Identification

Safety Data

  • [Risk Codes]
  • R36/37/38:Irritating to eyes, respiratory system and skin
  • [Safety Statements]
  • Hazard Symbols:
  • HazardClass:9

Properties

  • Molecular Weight:
  • 418.56622
  • Density:
  • 1.11 g/cm3
  • Boiling Point:
  • 564.9 °C at 760 mmHg
  • Melting Point:
  • 139 °C
  • Flash Point:
  • 184.8 °C
  • Alpha:
  • D25 +292° (c = 0.5% in acetonitrile)
  • Storage Temperature:
  • 0-6°C
  • Refractive index:
  • 1.53
  • Solubility:
  • H2O: Insoluble ;DMSO: ≥20mg/mL
  • Stability:
  • Simvastatin tablets should be stored at 5-30 deg C. When stored under these conditions, the tablets are stable for 24 months after the date of manufacture. The fixed-combination preparation containing simvastatin and ezetimibe should be stored in well-closed containers at 20-25 deg C.
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Question & Answer
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Simvastatin CAS 79902-63-9
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  • Description:Simvastatin, with the chemical formula C25H38O5, has the CAS number 79902-63-9. It is a white to off-white, crystalline powder with no distinct odor. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. Its basic structure co...
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  • Description:Whatsapp/Telegram:+ 86 13153699522 CAS No. 79902-63-9 Molecular formula C25H38O5 Molecular weight 418.57EINECS No. 616-751-8 Related categories
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simvastatin Cas 79902-63-9 from China
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  • Description:(1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste;7-beta,8-beta(2s*,4s*),8a-beta))-alph;butanoicacid,2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahy;Zocor, MK-733, Liponorm;Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR...
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Simvastatin CAS.79902-63-9
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  • Description:Quick Details Classification: Pharmaceutical Intermediates Cas NO.:79902-63-9 Name:Simvastatin Formula: C25H38O5 Boiling Point:
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SIMVASTATIN
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  • Description:Product NO: SP151 Simvastatin Basic information Lipid-lowering drugs Indications Chemical properties Uses Production methods Category Toxicity grading Acute toxicity Flammability hazard characteristics Storage characteristics Extinguishing agent
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