Antineoplastic Agents

Antineoplastic agents, often referred to as anticancer drugs or chemotherapy drugs, are a class of medications designed to treat and manage cancer. These agents work by targeting and interfering with the processes that allow cancer cells to grow, divide, and spread. Unlike normal cells, cancer cells tend to proliferate rapidly and uncontrollably. Antineoplastic agents are developed to specifically target and disrupt these abnormal growth patterns, with the goal of reducing or eliminating cancerous tumors.
Antineoplastic Agents categories
According to the effect of the drug, it can be divided into cytotoxic drugs and non-cytotoxic drugs. When traditional cytotoxic drugs kill cancer cells, they will also cause different damage to normal tissues and cells.
Pharmaceutical technology has advanced, leading to the evolution of antineoplastic drugs. These drugs have transitioned from non-selective and single cytotoxic drugs to more targeted and less harmful options. This advancement has ushered in a new era in the research and development of antineoplastic drugs. This has led to a new era in the research and development of antineoplastic drugs.
Usage of Antineoplastic Agents products
Antineoplastic Agents play a pivotal role in the realm of medical treatment. These agents are made to fight and stop the growth of cancer cells by targeting the complex mechanisms involved. Doctors use anticancer drugs in various cancer treatments, such as chemotherapy, targeted therapy, and immunotherapy, which makes them important in modern cancer care.
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Antineoplastic Agents X

Tamsulosin

Tamsulosin hydrochloride is the first in the class of potent and selective α- 1Aadrenoceptor antagonists introduced for the treatment of dysuria associated with benign prostatic hypertrophy (BPH). In a clinical study, significant improvement in irritative and obstructive symptoms has been reported ..
CAS No: 106133-20-4
Molecular Weight: 408.513
Molecular Formula:C₂₀H₂₈N₂O₅S
Density:1.191
Boiling Point:595.5 °C at 760 mmHg
Flash Point:313.9 °C

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Ondansetron hydrochloride

Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.Target: 5- HT3 ReceptorIC50 Value: in vitro: 5-HT evoked transient inward currents (EC50 = 3.4 microM; Hill coefficient = 1.8) that were blocked by the 5-HT3..
CAS No: 103639-04-9
Molecular Weight: 365.85
Molecular Formula:C₁₈H₂₄ClN₃O₃
Density:1.27
Boiling Point:546 oC at 760 mmHg
Flash Point:284 oC

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Streptozotocin

Streptozotocin, with the chemical formula C8H15N3O7, has the CAS number 18883-66-4. It is a naturally occurring chemical compound that is derived from the bacterium Streptomyces achromogenes. Streptozotocin appears as a white crystalline powder. It does not have a distinct odor. Its basic structure ..
CAS No: 18883-66-4
Molecular Weight: 265.222
Molecular Formula:C₈H₁₅N₃O₇
Density:1.86
Boiling Point:°Cat760mmHg
Flash Point:°C

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Isotretinoin

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.Target: RAR/RXRIsotretinoin has been the most effective and long-lasting drug for the..
CAS No: 4759-48-2
Molecular Weight: 300.442
Molecular Formula:C₂₀H₂₈O₂
Density:1.011
Boiling Point:462.8 °C at 760 mmHg
Flash Point:350.6 °C

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4-Cloromethyl-5-methyl-1,3-dioxol-2-one

4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.
CAS No: 80841-78-7
Molecular Weight: 148.542
Molecular Formula:C₅H₅ClO₃
Density:1.362
Boiling Point:163.2 oC at 760 mmHg
Flash Point:66.7 oC

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Omeprazole

Omeprazole(Prilosec) is a proton pump inhibitor used in the treatment of dyspepsia.Target: Proton PumpOmeprazole is a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger-Ellison syndrome. Omeprazole..
CAS No: 73590-58-6
Molecular Weight: 345.42
Molecular Formula:C₁₇H₁₉N₃O₃S
Density:1.37
Boiling Point:600 °C at 760 mmHg
Flash Point:9℃

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Lamivudine

Lamivudine, with the chemical formula C8H11N3O3S, has the CAS number 134678-17-4. It is a synthetic nucleoside analogue and antiviral medication. Lamivudine appears as a white to off-white crystalline powder. It has no distinct odor. The molecular structure of Lamivudine consists of a pyrimidine rin..
CAS No: 134678-17-4
Molecular Weight: 229.26
Molecular Formula:C₈H₁₁N₃O₃S
Density:1.73
Boiling Point:475.4°C at 760mmHg
Flash Point:9℃

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Pregabalin

Pregabalin is a chemical compound with the molecular formula C8H17NO2. It is a medication that falls under the class of anticonvulsant drugs. Pregabalin is a derivative of gamma-aminobutyric acid (GABA), a neurotransmitter in the central nervous system. Structurally, it is related to the inhibitory ..
CAS No: 148553-50-8
Molecular Weight: 159.22608
Molecular Formula:C₈H₁₇NO₂
Density:0.997
Boiling Point:274 °C at 760 mmHg
Flash Point:119.5 °C

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Allantoin

Colorless crystalline powder. Melting point is 238-240 ℃ (decomposition). Can be dissolved in hot water, hot alcohol and dilute sodium hydroxide solution, slightly soluble in water and alcohol, almost insoluble in ether and chloroform. Odorless, tasteless. In dry air is stable, prolonged boiling in..
CAS No: 97-59-6
Molecular Weight: 158.117
Molecular Formula:C₄H₆N₄O₃
Density:1.65
Boiling Point:478
Flash Point:230-234°C

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dipotassium tetrachloroplatinate

Dipotassium tetrachloroplatinate, with the chemical formula K2PtCl4, has the CAS number 10025-99-7. It appears as a yellow crystalline solid with no odor. The basic structure of dipotassium tetrachloroplatinate consists of two potassium ions (K+) and one tetrachloroplatinate ion (PtCl4-) in a crysta..
CAS No: 10025-99-7
Molecular Weight: 336.89
Molecular Formula:Cl₄K₂Pt
Density:3.38
Boiling Point:
Vapour density:

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Retinoic acid

Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.
CAS No: 302-79-4
Molecular Weight: 300.442
Molecular Formula:C₂₀H₂₈O₂
Density:1.011
Boiling Point:462.8 °C at 760 mmHg
Flash Point:350.6 °C

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Cytidine

Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.Target: Nucleoside antimetabolite/analogCytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N1-g..
CAS No: 65-46-3
Molecular Weight: 243.21662
Molecular Formula:C₉H₁₃N₃O₅
Density:0.9867 - 0.99809 (55 - 25 C)
Boiling Point:545.7°C at 760 mmHg
Flash Point:283.8°C

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CYTISINE

Cytisine is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus. Cytisine is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. has been used medically to help with smoking cessation[3]. Cytisine i..
CAS No: 485-35-8
Molecular Weight: 190.24166
Molecular Formula:C₁₁H₁₄N₂O
Density:1.24
Boiling Point:218℃ (2 mmHg)
Flash Point:203.6 °C

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Melanotan 1

Melanotan 1 is a chemical compound with the CAS number 75921-69-6. It is a synthetic analog of the hormone alpha-melanocyte-stimulating hormone (α-MSH). Melanotan 1 appears as a white to off-white powder with no distinct odor. Its molecular formula is C78H111N21O19. This compound is soluble in wate..
CAS No: 75921-69-6
Molecular Weight: 1646.84524
Molecular Formula:C₇₈H₁₁₁N₂₁O₁₉
Density:1.46

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2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride

white fine crystalline powderChEBI: A hydrochloride salt resulting from the reaction of equimolar amounts of ancitabine and hydrogen chloride. Ancitabine hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of ancitabine and hydrogen chloride. It has a role as an an..
CAS No: 10212-25-6
Molecular Weight: 225.20134
Molecular Formula:C₉H₁₂ClN₃O₄
Density:2.01
Boiling Point:442 °C at 760 mmHg
Flash Point:221.1 °C

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Naphazoline hydrochloride

White crystalline powder. Melting point 255-260 ℃. 40 grams of the product can be dissolved in 100 ml of water . It is soluble in alcohol, slightly soluble in chloroform, insoluble in ether and benzene. Odorless, bitter taste. White or almost white, crystalline powder.
CAS No: 550-99-2
Molecular Weight: 246.738
Molecular Formula:C₁₄H₁₅ClN₂
Density:1.15
Boiling Point:440.5 °C at 760 mmHg
Flash Point:220.2 °C

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Ketoconazole

Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.Target: CYP3A4 CYP24A1Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels,..
CAS No: 65277-42-1
Molecular Weight: 534.452
Molecular Formula:C₂₆H₂₈Cl₂N₄O₄
Density:139.11 cm³
Boiling Point:753.4 °C at 760 mmHg
Flash Point:409.4 °C

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Dimethyl sulfoxide

Dimethyl sulfoxide (abbreviated DMSO) is a sulfur-containing organic compound; molecule formula: (CH3) 2SO; It exhibits as colorless, odorless, hygroscopic and flammable transparent liquid at room temperature. It has both high polarity as well as high-boiling point. It also has aprotic and water-mis..
CAS No: 67-68-5
Molecular Weight: 78.13344
Molecular Formula:C₂H₆OS
Density:1.1
Boiling Point:189℃
Flash Point:95℃

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Amifostine

Amifostine is a broad-spectrum cytoprotection agent against the DNA damaging effects of ionizing radiation and chemotherapy drug. Solid Amifostine is an organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is use..
CAS No: 20537-88-6
Molecular Weight: 214.222961
Molecular Formula:C₅H₁₅N₂O₃PS
Density:1.367
Boiling Point:441.7 °C at 760 mmHg
Flash Point:220.9 °C

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Leuprorelin acetate

Leuprorelin acetate, with the chemical formula C59H84N16O12, has the CAS number 74381-53-6. It is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH). Leuprorelin acetate appears as a white to off-white powder with no distinct odor. Its basic structure consists of a peptide chain wit..
CAS No: 74381-53-6
Molecular Weight: 1269.46
Molecular Formula:C₆₁H₈₈N₁₆O₁₄
Density:1.44
Boiling Point:1720.5°C at 760 mmHg
Flash Point:994.3°C

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