Gastrointestinal agents

Gastrointestinal agents APIs (active pharmaceutical ingredients) are chemical compounds used in medications that affect the digestive system. These APIs are used to treat various gastrointestinal disorders and conditions such as acid reflux, peptic ulcers, irritable bowel syndrome, Crohn's disease, and inflammatory bowel disease.
The development of gastrointestinal agents APIs involves extensive research and testing to ensure their safety and efficacy. Once an API has been developed and tested, it can be used to manufacture a range of gastrointestinal medications that are prescribed to millions of patients worldwide.
Commonly Gastrointestinal agents products
Omeprazole: Omeprazole is a proton pump inhibitor (PPI) that is used to treat acid reflux and peptic ulcers.
Ranitidine: Ranitidine is an H2 receptor antagonist that is used to treat acid reflux and peptic ulcers.
Loperamide: Loperamide is an opioid receptor agonist that is used to treat diarrhea.
Mesalazine: Mesalazine is an anti-inflammatory drug that is used to treat inflammatory bowel disease and ulcerative colitis.
Domperidone: Domperidone is a dopamine receptor antagonist that is used to treat nausea and vomiting.
Metoclopramide: Metoclopramide is a dopamine receptor antagonist that is used to treat nausea and vomiting.
Esomeprazole: Esomeprazole is a proton pump inhibitor (PPI) that is used to treat acid reflux and peptic ulcers.
Usage of Gastrointestinal agents
These active pharmaceutical ingredients are vital chemical compounds incorporated into medications designed to impact the digestive system. By targeting various gastrointestinal disorders and conditions like acid reflux, peptic ulcers, irritable bowel syndrome, Crohn's disease, and inflammatory bowel disease, these APIs play a pivotal role in alleviating symptoms and promoting digestive health. Their inclusion in pharmaceutical formulations underscores their significance in the medical field, where they contribute to improved quality of life for individuals dealing with gastrointestinal issues.
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Gastrointestinal agents X

L-Glutamine

L-Glutamine is a non-essential amino acid present abundantly throughout the body and is involved in gastrointestinal disorders.Target: mGluRGlutamine (abbreviated as Gln or Q) is one of the 20 amino acids encoded by the standard genetic code. It is not recognized as an essential amino acid, but may ..
CAS No: 56-85-9
Molecular Weight: 146.1445
Molecular Formula:C₅H₁₀N₂O₃
Density:1.321
Boiling Point:445.6℃at760mmHg
Flash Point:185℃

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Omeprazole

Omeprazole(Prilosec) is a proton pump inhibitor used in the treatment of dyspepsia.Target: Proton PumpOmeprazole is a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, laryngopharyngeal reflux, and Zollinger-Ellison syndrome. Omeprazole..
CAS No: 73590-58-6
Molecular Weight: 345.42
Molecular Formula:C₁₇H₁₉N₃O₃S
Density:1.37
Boiling Point:600 °C at 760 mmHg
Flash Point:9℃

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Albendazole

Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.Target: AntiparasiticAlbendazole, marketed as Albenza (United States), Eskazole, Zentel, Andazol and Alworm, is a benzimidazole drug used for the treatment of a variety..
CAS No: 54965-21-8
Molecular Weight: 265.331
Molecular Formula:C₁₂H₁₅N₃O₂S
Density:1.3

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Praziquantel

It is white or almost white crystalline powder; it is odorless with a slightly bitter taste. It also has hygroscopic effect. Solubility (g/100m1): 9.7 in ethanol, 56.7 in chloroform, and 0.04 in water. It is easily soluble in dimethyl sulfoxide (DMSO), but insoluble in ether. It has a melting point ..
CAS No: 55268-74-1
Molecular Weight: 312.413
Molecular Formula:C₁₉H₂₄N₂O₂
Density:1.22
Boiling Point:544.1oCat 760 mmHg
Flash Point:254.6oC

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Cimetidine

Cimetidine, with the chemical formula C10H16N6S, has the CAS number 51481-61-9. It is a white to pale yellow crystalline powder with a faint characteristic odor. Cimetidine is a histamine H2-receptor antagonist that inhibits the production of stomach acid. Its basic structure consists of a pyrimidin..
CAS No: 51481-61-9
Molecular Weight: 252.33924
Molecular Formula:C₁₀H₁₆N₆S
Density:1.27
Boiling Point:488°Cat760mmHg
Flash Point:248.9°C

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Bisacodyl

Bisacodyl is a stimulant laxative drug that works directly on the colon to produce a bowel movement.Target: OthersBisacodyl is an organic compound that is used as a stimulant laxative drug. Bisacodyl (20 mg/kg) results in a decrease in AQP3 protein expression and increased mRNA expression level of T..
CAS No: 603-50-9
Molecular Weight: 361.39056
Molecular Formula:C₂₂H₁₉NO₄
Density:1.2
Boiling Point:492
Flash Point:252

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PARAFFIN

Clear colorless oil Mineral oil is a transparent, colorless, viscous oily liquid, withoutfluorescence in daylight. It is practically tasteless and odorless whencold, and has a faint odor of petroleum when heated.
CAS No: 8012-95-1
Molecular Weight: 338.696
Molecular Formula:C₁₅H₁₁ClO₇
Density:0.85 g/mL at 20 °C
Boiling Point:0° F (NIOSH, 2016)
Flash Point:380° F (USCG, 1999)

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Oxfendazole

Oxfendazole, with the chemical formula C15H13N3O3S, has the CAS number 53716-50-0. It is a benzimidazole anthelmintic drug used in veterinary medicine. Oxfendazole appears as a white to off-white crystalline powder with no distinct odor. Its basic structure consists of a benzimidazole ring attached ..
CAS No: 53716-50-0
Molecular Weight: 315.34702
Molecular Formula:C₁₅H₁₃N₃O₃S
Density:1.5
Boiling Point:529.8±50.0 °C at 760 mmHg (Predicted)
Flash Point:274.2±30.1 °C (Predicted)

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Rebeprazole sodium

Rebeprazole sodium is White Crystalline SolidRebeprazole sodium was launched as Pariet in Japan, its first market, for the treatment of peptic ulcers including gastric and duodenal ulcers. From 4-chloro- 2,3-dimethylpyridine N-oxide, a six step synthesis allows access to the basic skeleton after suc..
CAS No: 117976-90-6
Molecular Weight: 381.42447
Molecular Formula:C₁₈H₂₀N₃NaO₃S
Density:0.45~0.55 g/ml
Boiling Point:603.9 °C at 760 mmHg
Flash Point:319.1 °C

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Chlorhexidine diacetate

Chlorhexidine diacetate, with the chemical formula C26H38Cl2N10O4, has the CAS number 206986-79-0. It is a chemical compound that appears as a white or almost white powder. It has no distinct odor. The basic structure of Chlorhexidine diacetate consists of two acetate groups attached to a chlorhexid..
CAS No: 206986-79-0
Molecular Weight: 625.55
Molecular Formula:C₂₂H₃₀Cl₂N₁₀.₂C₂H₄O₂.xH₂O
Density:1.4±0.1 g/cm3 (Predicted)
Boiling Point:699.3ºC at 760 mmHg
Flash Point:376.7ºC

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Aluminum hydroxide

Aluminum hydroxide, with the chemical formula Al(OH)3, has the CAS number 21645-51-2. It appears as a white, odorless powder. The basic structure of aluminum hydroxide consists of one aluminum atom bonded to three hydroxide ions. This compound is insoluble in water. Aluminum hydroxide is considered ..
CAS No: 21645-51-2
Molecular Weight: 78.003
Molecular Formula:AlH₃O₃
Density:2.42 g/cm3 at 20 °C
Boiling Point:2980℃[at 101 325 Pa]

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Domperidone

Domperidone is a dopamine blocker and an antidopaminergic reagent.Target: Dopamine ReceptorDomperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability. Effectiveness and side-effects from domperidone may be influenced by patient-related factors in..
CAS No: 57808-66-9
Molecular Weight: 425.917
Molecular Formula:C₂₂H₂₄ClN₅O₂
Density:1.341
Boiling Point:723.6±70.0 °C at 760 mmHg
Flash Point:391.4±35.7 °C

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Racecadotril

Racecadotril (acetorphan), a potent enkephalinase inhibitor (IC50= 4.5 uM), protects endogenous enkephalins from degradation. IC50 value: 4.5 uMTarget: EnkephalinaseRacecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 uM. Unlike other medications used to treat diarrhea, ..
CAS No: 81110-73-8
Molecular Weight: 385.478
Molecular Formula:C₂₁H₂₃NO₄S
Density:1.206
Boiling Point:574.5 °C at 760 mmHg
Flash Point:301.2 °C

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1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester

CAS No: 881674-06-2
Molecular Weight: 233.24
Molecular Formula:C₁₃H₁₂FNO₂
Density:1.217±0.06 g/cm3 (20 oC 760 Torr)
Boiling Point:424.7±35.0 °C(Predicted)
Flash Point:210.7±25.9 °C

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Magnesium sulfate heptahydrate

Magnesium sulfate heptahydrate, with the chemical formula MgSO4·7H2O, has the CAS number 10034-99-8. It appears as a colorless crystal with no odor. The basic structure of magnesium sulfate heptahydrate consists of one magnesium atom, one sulfur atom, four oxygen atoms, and fourteen hydrogen atoms. ..
CAS No: 10034-99-8
Molecular Weight: 246.47
Molecular Formula:Mg.O₄S.₇H₂O
Density:2.66

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cis-5,8,11,14,17-Eicosapentaenoic acid-[19,19,20,20,20-D5]

CAS No: 1197205-73-4
Molecular Weight: 302.46
Molecular Formula:C₂₀H₃₀O₂
Density:0.958 g/mL at 25 °C
Boiling Point:439.3±24.0 °C at 760 mmHg
Flash Point:336.0±18.0 °C

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TAK-438

TAK-438, with the chemical formula C16H15F2N3O4S, has the CAS number 1260141-27-2. It is a pharmaceutical compound used for the treatment of gastric acid-related diseases. TAK-438 appears as a white to off-white powder with no distinct odor. Its basic structure consists of a benzimidazole ring attac..
CAS No: 1260141-27-2
Molecular Weight: 461.46300
Molecular Formula:C₂₁H₂₀FN₃O₆S

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Esomeprazole sodium

Esomeprazole sodium, with the chemical formula C17H18N3NaO3S, has the CAS number 161796-78-7. It is a medication that belongs to the class of proton pump inhibitors (PPIs). Esomeprazole sodium appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. Its bas..
CAS No: 161796-78-7
Molecular Weight: 367.399
Molecular Formula:C₁₇H₁₈N₃NaO₃S
Boiling Point:600 °C at 760 mmHg
Flash Point:316.7 °C

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Esomeprazole magnesium

ChEBI: A magnesium salt resulting from the formal reaction of magnesium hydroxide with 2 mol eq. of esomeprazole. An inhibitor of gastric acid secretion, it is used for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zolli ger-Ellison syndrome.Esomeprazole ma..
CAS No: 161973-10-0
Molecular Weight: 713.12100
Molecular Formula:C₃₄H₃₆MgN₆O₆S₂
Boiling Point:600ºC at 760 mmHg
Flash Point:316.7ºC

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2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]thio]-6-(1H-pyrrol-1-yl)-1H-benzimidazole

CAS No: 172152-35-1
Molecular Weight: 350.43742
Molecular Formula:C₁₉H₁₈N₄OS
Density:1.30±0.1 g/cm3(Predicted)
Boiling Point:590.4±60.0 °C(Predicted)
Flash Point:310.9±32.9 °C (Predicted)

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Gastrointestinal agents

Commonly Gastrointestinal agents products

Usage of Gastrointestinal agents