Z-PRO-OSU
- Iupac Name：1-O-benzyl 2-O-(2,5-dioxopyrrolidin-1-yl) (2S)-pyrrolidine-1,2-dicarboxylate
- CAS No.: 3397-33-9
- Molecular Weight：346.339
- Modify Date.: 2022-11-29 11:29
1. Names and Identifiers
- 1.1 Name
- Z-PRO-OSU
- 1.2 Synonyms
2,5-Dioxo-1-pyrrolidinyl 1-[(benzyloxy)carbonyl]-L-prolinate 2,5-Dioxopyrrolidin-1-yl 1-[(benzyloxy)carbonyl]-L-prolinate Benzyl (S)-2-(((2,5-dioxo-1-pyrrolidinyl)oxy)carbonyl)pyrrolidine-1-carboxylate BENZYLOXYCARBONYL-L-PROLINE N-HYDROXYSUCCINIMIDE ESTER CBZ-L-PROLINE HYDROXYSUCCINIMIDE ESTER Cbz-proline N-hydroxysuccinimide ester CBZ-Pro-Osu ester de N-hydroxysuccinimide de N-carbobenzoxy-L-proline L-Proline, 1-[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester N-benzyloxycarbonyl-L-proline N-hydroxysuccinimido ester N-Benzyloxycarbonylprolin-hydroxysuccinimidester N-carbobenzoxy-L-proline N-succinimidyl ester N-CBZ-L-PROLINE N-HYDROXYSUCCINIMIDE ESTER S-Z-proline-hydroxysuccinimide ester Z-L-PROLINE HYDROXYSUCCINIMIDE ESTER Z-L-PROLINE N-HYDROXYSUCCINIMIDE ESTER Z-L-Pro-OSu Z-proline N-hydroxysuccinimide ester Z-PROLINE-OSU
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- 1.3 CAS No.
- 3397-33-9
- 1.4 CID
- 853482
- 1.5 EINECS(EC#)
- 222-255-9
- 1.6 Molecular Formula
- C17H18N2O6 (isomer)
- 1.7 Inchi
- InChI=1S/C17H18N2O6/c20-14-8-9-15(21)19(14)25-16(22)13-7-4-10-18(13)17(23)24-11-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11H2/t13-/m0/s1
- 1.8 InChIkey
- BDNYCEKWUBRCBJ-ZDUSSCGKSA-N
- 1.9 Canonical Smiles
- C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)ON3C(=O)CCC3=O
- 1.10 Isomers Smiles
- C1C[C@H](N(C1)C(=O)OCC2=CC=CC=C2)C(=O)ON3C(=O)CCC3=O
2. Properties
- 2.1 Density
- 1.4
- 2.1 Melting point
- 88-90 °C
- 2.1 Boiling point
- 502.2°Cat760mmHg
- 2.1 Refractive index
- 1.608
- 2.1 Flash Point
- 257.5°C
- 2.1 Precise Quality
- 346.11600
- 2.1 PSA
- 93.22000
- 2.1 logP
- 1.27060
- 2.1 Storage
- -15°C
- 2.2 StorageTemp
- Inert atmosphere,2-8°C
3. Safety and Handling
- 3.1 Risk Statements
- 22-24/25
- 3.1 Safety Statements
- 22-24/25
4. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
no data available
2.2 GHS label elements, including precautionary statements
| Pictogram(s) | no data available |
| Signal word | no data available |
| Hazard statement(s) | no data available |
| Precautionary statement(s) | |
| Prevention | no data available |
| Response | no data available |
| Storage | no data available |
| Disposal | no data available |
2.3 Other hazards which do not result in classification
no data available
6. Synthesis Route
3397-33-9Total: 4 Synthesis Route
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Literatures:
Il'ina, A. V.; Davidovich, Yu. A.; Rogozhin, S. V.; Moiseenkov, A. M. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, p. 1067 - 1070 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 5 p. 1163 - 1165
Yield: ~88%
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Literatures:
Griffin, Martin; Mongeot, Alexandre; Collighan, Russell; Saint, Robert E.; Jones, Richard A.; Coutts, Ian G.C.; Rathbone, Daniel L. Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 20 p. 5559 - 5562
Yield: null
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8. Computational chemical data
- Molecular Weight: 346.339g/mol
- Molecular Formula: C17H18N2O6
- Compound Is Canonicalized: True
- XLogP3-AA: 1.2
- Exact Mass: 346.11648630
- Monoisotopic Mass: 346.11648630
- Complexity: 541
- Rotatable Bond Count: 6
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 6
- Topological Polar Surface Area: 93.2
- Heavy Atom Count: 25
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count: 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 1
- CACTVS Substructure Key Fingerprint: AAADceB7OAAAAAAAAAAAAAAAAAAAAWLAAAAwAAAAAAAAAAABAAAAHgAEAAAADCjhmAYwCIMQBACIAiHSGAACAAAgAAAoiAGICIgKJjKAsTiMMAAkxiGYqAed0SIOAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==
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