CAS 25952-53-8 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride | Products & Prices & Suppliers

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, with the chemical formula C8H17N3·HCl, has the CAS number 25952-53-8. It is a white to off-white crystalline powder with a faint odor. The basic structure of this chemical consists of a carbodiimide group attached to a 3-dimethylaminopropyl group and an ethyl group. It is sparingly soluble in water. Safety information indicates that this compound may cause skin and eye irritation. It is also harmful if swallowed or inhaled. Precautions should be taken to avoid contact with skin, eyes, and clothing. In case of ingestion, immediate medical attention is required. This chemical should be handled in a well-ventilated area and with appropriate protective equipment.

Applicable Fields

Bioconjugation: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is commonly used in bioconjugation reactions. Its purpose in this field involves the activation of carboxyl groups in biomolecules, allowing them to react with amino groups. The mechanism of action in bioconjugation is the formation of amide bonds between the activated carboxyl groups and the amino groups, resulting in the covalent attachment of biomolecules.

Peptide synthesis: This compound is widely used in peptide synthesis. Its purpose in this field is to activate carboxyl groups in amino acids, facilitating their coupling with other amino acids to form peptide bonds. The mechanism of action in peptide synthesis involves the formation of amide bonds between the activated carboxyl groups and the amino groups of the incoming amino acids, leading to the stepwise elongation of the peptide chain.

Storage

Conditions: Store in a cool and dry place.