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Antibiotic and antimicrobial agents

Antibiotics are a kind of secondary metabolites with anti-pathogens or other activities produced by microorganisms or higher animals and plants in the course of life, which can interfere with the development function of other living cells. Antibiotics mainly play an inhibitory or bactericidal effect on bacteria but not in human or other animals and plants, including four major mechanisms, including inhibition of bacterial cell wall synthesis, enhancement of bacterial cell membrane permeability, interference of bacterial protein synthesis and inhibition of bacterial nucleic acid replication and transcription. According to the chemical structure, antibiotics can be divided into quinolone antibiotics, β-lactam antibiotics, macrolides, aminoglycoside antibiotics and so on. According to their uses, they can be divided into antibacterial antibiotics, antifungal antibiotics, antiviral antibiotics, agricultural antibiotics and other microbial drugs.

Antimicrobial agents refer to chemicals that can keep the growth or reproduction of some microorganisms (bacteria, fungi, yeasts, algae and viruses, etc.) below the necessary level within a certain period of time, with bacteriostatic and bactericidal functions. Generally, it can be divided into inorganic antimicrobial agents, organic antimicrobial agents and natural antimicrobial agents. Silver ion antimicrobial agents play a leading role in inorganic antimicrobial agents, as well as zinc oxide, copper oxide and so on; organic antimicrobial agents have poor heat resistance, easy hydrolysis and short validity; natural antimicrobials are mainly extracted from natural plants, such as mustard, although they are easy to use, but their antibacterial effect is limited, heat resistance is poor, bactericidal rate is low and the quantity is small.

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Acyclovir; 59277-89-3 structural formula
Acyclovir
  • Acyclovir, a molecule tailored to inactivate the thymidine kinase of the herpesvirus, is a guanosine analogue antiviral drug. It is a drug for HSV infection by GlaxoSmithKline.IC50 Value: 0.53-0.75 uM [3]Target: HSVin vitro: Acyclovir sensitivity was determined in a plaque-reduction assay in Vero ce..
  • CAS No: 59277-89-3
  • Molecular Weight: 225.20464
  • Molecular Formula:C8H11N5O3
  • Density:1.77
  • Boiling Point:595 °C at 760 mmHg
  • Flash Point:595 °C at 760 mmHg
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 596 Suppliers Request For Quotation
Azithromycin; 83905-01-5 structural formula
Azithromycin
  • Azithromycin, with the chemical formula C38H72N2O12, has the CAS number 83905-01-5. It is a macrolide antibiotic used to treat a variety of bacterial infections. Azithromycin appears as a white to off-white crystalline powder. It has no distinct odor. The basic structure of Azithromycin consists of ..
  • CAS No: 83905-01-5
  • Molecular Weight: 748.996
  • Molecular Formula:C38H72N2O12
  • Density:1.18
  • Boiling Point:822.1 °C at 760 mmHg
  • Flash Point:451 °C
Encyclopedia Safety and Handling MSDS Synthesis Route 526 Suppliers Request For Quotation
Chloramphenicol; 56-75-7 structural formula
Chloramphenicol
  • Chloramphenicol is a broad-spectrum antibiotic.Target: AntibacterialChloramphenicol is a bacteriostatic drug that stops bacterial growth by inhibiting protein synthesis. Chloramphenicol prevents protein chain elongation by inhibiting the peptidyl transferase activity of the bacterial ribosome. It sp..
  • CAS No: 56-75-7
  • Molecular Weight: 323.12938
  • Molecular Formula:C11H12Cl2N2O5
  • Density:1.547
  • Boiling Point:644.9 oC at 760 mmHg
  • Flash Point:343.8 oC
Encyclopedia Safety and Handling MSDS NMR Spectrum 501 Suppliers Request For Quotation
Curcumin; 458-37-7 structural formula
Curcumin
  • Curcumin is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase ((HATs)) and also shows inhibitory effects on NF-κB and MAPKs. Curcumin ..
  • CAS No: 458-37-7
  • Molecular Weight: 368.385
  • Molecular Formula:C21H20O6
  • Density:1.279
  • Boiling Point:591.4 °C at 760 mmHg
  • Flash Point:208.9 °C
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 483 Suppliers Request For Quotation
Terbinafine Hydrochloride; 78628-80-5 structural formula
Terbinafine Hydrochloride
  • Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM.
  • CAS No: 78628-80-5
  • Molecular Weight: 327.896
  • Molecular Formula:C21H26ClN
  • Density:1.007
  • Boiling Point:417.9 oC at 760 mmHg
  • Flash Point:183.7 oC
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 522 Suppliers Request For Quotation
(3S,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,3S)-4,6-diamino-2-[(3R,4S)-4-[(2R,3R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid; 1405-10-3 structural formula
(3S,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,3S)-4,6-diamino-2-[(3R,4S)-4-[(2R,3R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid
  • (3S,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,3S)-4,6-diamino-2-[(3R,4S)-4-[(2R,3R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid (CAS 1405-10-3) is a complex compound with a molecular formula of C2..
  • CAS No: 1405-10-3
  • Molecular Weight: 712.72
  • Molecular Formula:C23H48N6O17S
  • Flash Point:56℃
Encyclopedia Safety and Handling MSDS NMR Spectrum 449 Suppliers Request For Quotation
Voriconazole; 137234-62-9 structural formula
Voriconazole
  • Cyrstalline SolidVoriconazole was introduced in the US for the treatment of acute invasive aspergillosis, candidosis and other emerging fungal infections seen in immuno compromised patients. It can be synthesized in 3 steps by reaction of readily available 6-( 1 -bromoethyl)-4-chloro-5 fluoropyrimid..
  • CAS No: 137234-62-9
  • Molecular Weight: 349.317
  • Molecular Formula:C16H14F3N5O
  • Density:1.42
  • Boiling Point:508.6°C at 760 mmHg
  • Flash Point:261.4°C
Encyclopedia Safety and Handling MSDS Synthesis Route 432 Suppliers Request For Quotation
Fluconazole; 86386-73-4 structural formula
Fluconazole
  • Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.Target: AntifungalFluconazole is a triazole antifungal intended for oral treatment of superficial and systemic mycoses. In tests done in standard mycological media, the compou..
  • CAS No: 86386-73-4
  • Molecular Weight: 306.270786
  • Molecular Formula:C13H12F2N6O
  • Density:1.49
  • Boiling Point:579.8 oC at 760 mmHg
  • Flash Point:304.4 oC
Encyclopedia Safety and Handling MSDS Synthesis Route 486 Suppliers Request For Quotation
Norfloxacin; 70458-96-7 structural formula
Norfloxacin
  • It is white to light yellow crystalline powder. It is odorless with slightly bitter taste. Upon exposure to the air, it can easily absorb moisture to form a hemihydrate. Its color will be deepened upon light. Solubility (mg/m1) in 25 ℃: 0.28 in water, 0.98 in methanol, 1.9 in ethanol, 5.1 in aceton..
  • CAS No: 70458-96-7
  • Molecular Weight: 319.330823
  • Molecular Formula:C16H18FN3O3
  • Density:1.344
  • Boiling Point:555.8 °C at 760 mmHg
  • Flash Point:289.9 °C
Encyclopedia Safety and Handling MSDS Synthesis Route 419 Suppliers Request For Quotation
Fluorocytosine; 2022-85-7 structural formula
Fluorocytosine
  • A fluorinated pyrimidine, 5-flucytosine (fluorocytosine; 5-FC, Fig. 1), was initially developed as a potential anti-cancer agent but it was not sufficiently effective in the field of cancer chemotherapy[1]. Later, 5-FC proved to be active in experimental candidiasis and cryptococcosis in mice[2] and..
  • CAS No: 2022-85-7
  • Molecular Weight: 129.094
  • Molecular Formula:C4H4FN3O
  • Density:1.73
  • Boiling Point:298
  • Flash Point:296
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 393 Suppliers Request For Quotation
Clindamycin phosphate; 24729-96-2 structural formula
Clindamycin phosphate
  • Clindamycin phosphate is an antibiotic, which blocks the ribosomes of microorganisms. It is usually used to treat infections with anaerobic bacteria, can also be used to treat protozoal diseases, such as malaria.
  • CAS No: 24729-96-2
  • Molecular Weight: 504.96
  • Molecular Formula:C18H34ClN2O8PS
  • Density:1.41 g/cm3
  • Boiling Point:159°C
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 371 Suppliers Request For Quotation
1,2-Benzisothiazol-3(2H)-one; 2634-33-5 structural formula
1,2-Benzisothiazol-3(2H)-one
  • 1,2-Benzisothiazol-3(2H)-one, with the chemical formula C7H5NOS, has the CAS number 2634-33-5. It appears as a white to light yellow crystalline powder with a slight odor. The basic structure of 1,2-Benzisothiazol-3(2H)-one consists of a benzene ring fused with an isothiazole ring, with an oxygen at..
  • CAS No: 2634-33-5
  • Molecular Weight: 151.183
  • Molecular Formula:C7H5NOS
  • Density:1.367
  • Boiling Point:204.5 oC at 760 mmHg
  • Flash Point:77.5 oC
Encyclopedia Safety and Handling MSDS NMR Spectrum 378 Suppliers Request For Quotation
Gentamycin sulfate; 1405-41-0 structural formula
Gentamycin sulfate
  • Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. It inhibits DNase I with an IC50 of 0.57 mM.
  • CAS No: 1405-41-0
  • Molecular Weight: 1506.8
  • Molecular Formula:C60H127N15O26S
  • Density:1.000 g/cm3
  • Boiling Point:797.6 °C at 760 mmHg
  • Flash Point:436.2 °C
Encyclopedia Safety and Handling MSDS NMR Spectrum 410 Suppliers Request For Quotation
Trimethoprim; 738-70-5 structural formula
Trimethoprim
  • Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections.Target: DHFRTrimethoprim (TMP), an inhibitor of dihydrofolate reductase, decreases the level of tetrahydrofolate supplying one-carbon units for biosynthesis of nucleotides, proteins, ..
  • CAS No: 738-70-5
  • Molecular Weight: 290.323
  • Molecular Formula:C14H18N4O3
  • Density:1.252
  • Boiling Point:526 oC at 760 mmHg
  • Flash Point:271.9 oC
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 367 Suppliers Request For Quotation
Chlorhexidine Diacetate; 56-95-1 structural formula
Chlorhexidine Diacetate
  • Chlorhexidine Diacetate (CAS 56-95-1) is a chemical compound that is commonly used for its antimicrobial properties. It appears as a white crystalline powder and has a basic structure consisting of chlorhexidine cations and diacetate anions. This compound is soluble in water and forms a clear soluti..
  • CAS No: 56-95-1
  • Molecular Weight: 505.45
  • Molecular Formula:C26H38Cl2N10O4
  • Density:1.0±0.1 g/cm3 (Predicted)
  • Boiling Point:194.8±13.0 °C at 760 mmHg (Predicted)
  • Flash Point:73.0±15.3 °C (Predicted)
Encyclopedia Safety and Handling MSDS NMR Spectrum 346 Suppliers Request For Quotation
Rifampicin; 13292-46-1 structural formula
Rifampicin
  • Red to Orange Crystalline SolidChEBI: A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei)
  • CAS No: 13292-46-1
  • Molecular Weight: 822.953
  • Molecular Formula:C43H58N4O12
  • Density:1.34
  • Boiling Point:1004.42 °C at 760 mmHg
  • Flash Point:561.253 °C
Encyclopedia Safety and Handling MSDS Synthesis Route 365 Suppliers Request For Quotation
Itraconazole; 84625-61-6 structural formula
Itraconazole
  • Itraconazole is a triazole antifungal agent.IC50 Value: N/ATarget: antifungalin vitro: Itraconazole is pharmacologically distinct from other azole antifungal agents in that it is the only inhibitor in this class that has been shown to inhibit both the hedgehog signaling pathway and angiogenesis[1, 2..
  • CAS No: 84625-61-6
  • Molecular Weight: 705.641
  • Molecular Formula:C35H38Cl2N8O4
  • Density:1.4
  • Boiling Point:850 oC at 760 mmHg
  • Flash Point:467.9 oC
Encyclopedia Safety and Handling MSDS Synthesis Route 394 Suppliers Request For Quotation
Ofloxacin; 82419-36-1 structural formula
Ofloxacin
  • Ofloxacin is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase.Target: DNA gyrase Ofloxacin is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. In vitro it has a broad spectrum of activity against aerobic Gram-negative..
  • CAS No: 82419-36-1
  • Molecular Weight: 361.37
  • Molecular Formula:C18H20FN3O4
  • Density:1.2688 (estimate)
  • Boiling Point:571.5°Cat760mmHg
  • Flash Point:299.4°C
Encyclopedia Safety and Handling MSDS Synthesis Route 334 Suppliers Request For Quotation
Isoniazid; 54-85-3 structural formula
Isoniazid
  • Isoniazid is an antibacterial agent used primarily as a tuberculostatic.Target: AntibacterialIsoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M. tuberculosis is called KatG [1]. KatG couples the isonicotinic acyl with NADH to form isonicotinic acyl-NADH ..
  • CAS No: 54-85-3
  • Molecular Weight: 137.14
  • Molecular Formula:C6H7N3O
  • Density:1.2620 (rough estimate)
  • Boiling Point:251.97°C (rough estimate)
  • Flash Point:>250°C
Encyclopedia Safety and Handling MSDS NMR Spectrum 354 Suppliers Request For Quotation
Levofloxacin hydrochloride; 100986-85-4 structural formula
Levofloxacin hydrochloride
  • Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.Target: AntibacterialLevofloxacin reduced bacterial load compared with placebo by 4.9-fold (95% confidence interval, 1.4-25.7; P=0.02) at day..
  • CAS No: 100986-85-4
  • Molecular Weight: 361.373
  • Molecular Formula:C18H20FN3O4
  • Density:1.48
  • Boiling Point:571.5°Cat760mmHg
  • Flash Point:299.4°C
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 344 Suppliers Request For Quotation
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