Argireline Low price high purity

Classification: Hormones and synthetic substitutes

Cas NO.: 616204-22-9

Name: Argireline

Molecular Formula: C34H60N14O12S

Refractive index:1.66

Purity: 99%

usage: ), also known as Botoxin-like, is an oligopeptide that mimics the 6 amino acids

Brand Name: xingbei

EINECS: 1592732-453-0

Aliase: Ac-Glu-Glu-Met-Glu-Arg-Arg-NH2;N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide;AcetylHexapeptide-3/ChemicalbookAcetylHexapeptide-8;Argireline,Acetylhexapeptide-3,BR;Anti-WrinkleMulti-Peptides;Reproage;Argireline;ArgirelineacetateAc-Glu-Glu-Met-Arg-Arg-NH2

Purity: 99%

Appearance:White powder/bottle

Brand: xingbei

Packaging Detail: bottle/Aluminum foil bag/Customized to your needs

Delivery Detail: Goods will be delivered immediately upon receipt of payment

Argireline, also known as Botox, is an oligopeptide 1 that mimics the 6 amino acids of the N-terminal of SNAP-25 protein. Acirirelin is one of the ingredients commonly used in high-end cosmetics. It is mainly used to reduce wrinkles caused by the contraction of facial expression muscles, and has an ideal effect on the forehead or wrinkles around the eyes. Akirurelin is a safer, cheaper and milder alternative to Botox. Acyrelin competes for the site of SNAP-25 in the melt-bubble complex, thus affecting the formation of the melt-bubble complex, resulting in the inability of vesicles to effectively release neurotransmitters, weakening muscle contraction, thus relaxing muscles, soothing fine lines and making skin clear and flawless, and promoting cell regeneration to restore softness and elasticity of skin. Therefore, it is widely used in the preparation of cosmetics and health products. Argireline, also known as Botox, is an oligopeptide 1 that mimics the 6 amino acids of the n-terminal of SNAP-25 protein. Acirirelin is one of the ingredients commonly used in high-end cosmetics. It is mainly used to reduce wrinkles caused by the contraction of facial expression muscles, and has an ideal effect on the forehead or wrinkles around the eyes. In addition, it also promotes the production of collagen, which helps to rebuild skin tissue. The active hexapeptide, also known as Akirylin, is an oligopeptide that mimics the N-terminal of SNAP-25 protein and consists of six amino acids. Hexapepin inhibits SNARE receptor synthesis, inhibits excessive release of catecholamines and acetylcholine in skin, locally blocks nerve transmitting muscle contraction signals, and relaxes facial muscles to soothe fine lines. The preparation method of acirirelin comprises the following steps: Step 1: take the resin, activate it, and obtain the amino resin; Step 2: Take the amino resin obtained in step 1, and first step by step couple guanidine-protected L-arginine, guanidine-protected L-arginine, and side-chain amino protected L-glutamine to obtain a tripeptide resin; Step 3: Take the tripeptide resin obtained in step 2, and in the second step, couple L-methionine, L-glutamic acid protected by side chain carboxyl group and N-acetyl-L-glutamic acid protected by side chain carboxyl group to obtain hexapeptide resin; Step 4: hexapeptide resin obtained by cracking step 3, the first product is obtained; Step 5: Take the first product obtained in step 4, purify it, and get it. Bioactive Argireline (AChemicalbookcetylhexapeptide - 3) is a kind of non-toxic, can penetrate the skin anti-wrinkle peptide. Argireline significantly inhibits Ca2+ -dependent neurotransmitter release at the neuromuscular junction. Argireline has anti-wrinkle and anti-aging properties. In vitro studies TheincubationofArgirelinesolutionindifferentconcentrationswithhumanembryonickidneyHEK - 293 (IC50of34. 862 microns) andneurobla StomaIMR - 32 cells (IC50of68. 458 microns)) for48hhavedosedependentantiproliferativeeffect. Argirelinesolutionincubatedindifferentco ncentrationswithHSFhasadose-dependentantiproliferativeeffectonthosecells.CellularproliferationisnoteffectedinArgirelinel owconcentration. In vivo study Argirelineisappliedtotheagedmicetwicedailyfor6weeks Thereisanimprovementinthehistologicalstructureofskintissueinthea gedmice; theamountoftypeIcollagenfibersincreased,whilethatoftypeIIIcollagenfibersdecreased.Argirelinecouldimprovethehistologicals tructureofskintissueandrejuvenatetheagingskin.