How to effectively combine Adapalene and Ren Er acid for optimal skin benefits?

Adapalene and Ren Er acid are two effective skin care components, each with the characteristics of anti -acne and anti -inflammatory. Understanding how to use them can help improve skin state and achieve more ideal skin care effects.

Introduction:

( 1)

topical vitamin A derivatives vitamin A has been used to treat acne for nearly thirty years. They are the most effective acne solubitives for treating ordinary acne, which can reduce the formation and quantity of micro acne through normalization or even increased desquamation process. They also promote the clearance of the previous existence of acne and reduce pustule pustules. Adapalene gel is the third -generation vitamin A -acid drug, which has the effects of improving the keratinization of hair follicle sebaceous gonads, dissolving microcomas and acne, anti -inflammatory, pigmentation and scar after improving acne.

Adapalene ( adapalene) is a synthetic tarache acid derivative with retinol -like activity. ADAPALENE's chemical name is 6- [3- (1-diamond alkyl) -4-methaxyl benzhenyl] -2-pyrite. Adapalene is a kind of white to gray -white powder, soluble in tetrahydrocarbu, slightly soluble in ethanol, almost insoluble in water. Molecular formula is C28H28O3 molecular weight is 412.52. adapalene's structure is as follows:

( 2)

Ren Er acid ( AZA) is an organic compound with a molecular formula HOOC (CH2) 7COOH. This saturated di carboxylic acid exists in the form of white powder. It exists in wheat, rye and barley. It is the precursor of various industrial products, including polymers and plasticizers, and is also part of many hair and skin conditioning agents. Ren two is used to treat mild to medium acne, including acne acne and inflammatory acne. It belongs to a category of drugs called di carboxylic acid. It works by killing acne bacteria infected with skin pores. It also reduces the generation of keratin, and keratin is a natural substance that promote the growth of acne bacteria. Ren two is also used as a local gel treatment for the rosacea because it can reduce inflammation. It can remove the masses and swelling caused by the rosacea. The structure of Ren two acidic acid is as follows:

1. Can I use Ren diexide with adapalene?

The combination of Ren dices and adapalene shows a coordinated role in the treatment of acne, which can more effectively improve the symptoms of acne. However, because these two ingredients have a certain irritation, when using other ingredients such as AHA or salicylic acid, it may increase skin irritation when used at the same time. Although Ren diexin and adapalene have potential effects, it may cause the skin to dry, burns, tingling, redness, and peeling when used in combination. It is recommended to consult a dermatologist before use to obtain professional guidance suitable for your skin type.

So use adapalene or eryosicide? For sensitive skin, it is recommended to apply Ren Er acid first, because it is usually regarded as a gentle choice. If your skin is not so sensitive, you can choose any of these two ingredients first, but it is usually recommended to use adapalene after using Ren dietic acid.

2. adapalene or Ren Er acid?

( 1) adapalenevs Ren di -acid treatment acne: comparative effect

More and more adult acne is difficult to treat or recur after adolescence, so it is necessary to find a safe and effective treatment plan for this kind of trouble. Evaluation 15%Ren Diexicate Gel (AZA) and the curative effect of non -therapy in the maintenance treatment of female adult acne, and compare it with 0.1%Adapalene gel (AD) The efficacy and safety of 6 months). This researcher's blind method was included in 55 women aged 18 to 45 years old with adult acne and randomly divided into three groups. They accepted AZA gel for 9 months per day (AZA9M, N = 17) Or AZA gel was treated twice a day for 3 months, and then a 6 -month observation period (AZA3M, N = 19) or AD gel for 9 months per day (AD9m, N = 19). The parameters of the efficacy, safety and patient related factors were analyzed.

A Thielitz and others studied that AZA15%gel is a safe and effective treatment and maintenance method. The effect of controlling inflammatory acne is not inferior to AD 0.1%gel. Studies have shown that 15% Ren di -acid gel and 0.1% Adapalene gel have roughly the same effectiveness.

( 2) Ren diexic acid vsadapalene treatment pigmentation: Which is better?

Rener acid is used to treat skin pigmentation, including excessive pigmentation after melasma and inflammation, especially those with darker skin tone. It has been recommended as a substitute for phenylphenol. As a tyrosinase inhibitor, Renxin acid will reduce the synthesis of melanin.

W K Jacek et al. Evaluation 0.1% Topical adapalene gel treats the efficacy and safety of ordinary acne in South Africa patients. South African blacks in 65 years between the 65-year-old ADAPALENE gels were conducted in the 12-week. All patients suffer from mild to moderate facial acne defined by the Leeds scoring system; they are instructed to apply drugs once a day. Rating the number and severity of the lesion in the 4th, 8th and 12th weeks. Studies have found that 0.1%Adapalene gel is an effective and tolerated black local treatment drug. It can reduce inflammation and non -inflammatory lesions, and prevent and relieve acne -related pigmentation.

Both Ren dices and adapalene are effective local drugs for treating pigmentation. But the principle of their role is slightly different. Your dermatologist can recommend which method is more suitable according to your pigmentation type.

3. Suggestions

When combining adapalene and Rener acid, although these two ingredients have significant skin care effects, the specific methods and frequencies still need to be based on personal skin. In order to ensure safety and effectiveness, it is recommended to consult a doctor or dermatologist before starting use to obtain professional guidance and avoid possible stimulus and adverse reactions.

refer to:

[1] https://en.wikipedia.org/wiki/azlaic_acid

[2] https://pubmed.ncbi.nlm.nih.gov/25399481/

[3] https://onlinelibrary.wiley.com/doi/10.1111/jdv.12823

[4] https://pubmed.ncbi.nlm.nih.gov/11843232/

[5] https://www.sciencedirect.com/topics/neuroscience/adapalene

[6] https://www.ncbi.nlm.nih.gov/pmc/articleS/pmc3663177//

[7] https://www.ncbi.nlm.nih.gov/pmc/articleS/pmc8776661//

[8] https://www.ncbi.nlm.nih.gov/pmc/articles/pmc2374937//

[9] Luo Qin. Acne Artifact -Adapalene Gel [J]. Family medicine, 2024, (06): 25.