CAS 321596-55-8 4,6-Dibromo-3-hydroxypyridine-2-carboxylic acid methyl ester | Products & Prices & Suppliers

At room temperature, BrTo magnetically stirred 33 wt percent hydrogen bromide (10.00 ml, 55.2 mmol) in acetic acid was added methyl 2-(((benzyloxy)carbonyl)amino)-2-(furan-2-yl)acetate (2.89 g, 10 mmol). After stirring at room temperature for 1 hr, 150 mL of anhydrous ether was added to give 2.34 g of a grey solid. To a magnetically stirred solution of this grey solid and sodium acetate (3.53 g, 43.0 mmol) in 100 mL of water at 0° C. was added dropwise of a solution of bromine (2.215 ml, 43.0 mmol) in 20 mL of MeOH. over 30 min. After stirring at room temperature, the reaction mixture was filtered through a fritted glass funnel. The off-white solid was dissolved in 75 mL of CH