CAS 24939-03-5 Polyinosinic acid-polycytidylic acid | Products & Prices & Suppliers

Polyinosinic acid-polycytidylic acid, also known as poly(I:C), is a synthetic double-stranded RNA molecule. It has the CAS number 24939-03-5. Poly(I:C) appears as a white to off-white powder. It does not have a distinct odor. The basic structure of poly(I:C) consists of repeating units of inosinic acid and cytidylic acid. The molecular formula of poly(I:C) is (C10H12N5O7P)n. Poly(I:C) is soluble in water.

Safety Information

Poly(I:C) is generally considered to be safe for use. However, it is important to handle this chemical with care and follow proper safety precautions. It is recommended to wear protective gloves and eyewear when working with poly(I:C). In case of ingestion, seek medical attention immediately. Poly(I:C) may cause irritation to the skin and eyes. It is advisable to avoid direct contact with the chemical.

Applicable Fields

Poly(I:C) has various applications in the field of immunology and virology. It is commonly used as a research tool to study the immune response and antiviral mechanisms. Poly(I:C) is known to activate the innate immune system and stimulate the production of interferons and other cytokines. It is used to mimic viral infection in laboratory experiments and to investigate the immune response to viral pathogens.

Mechanism of Action

The mechanism of action of poly(I:C) involves its ability to activate toll-like receptor 3 (TLR3) and melanoma differentiation-associated protein 5 (MDA5) receptors. Upon binding to these receptors, poly(I:C) triggers a signaling cascade that leads to the production of interferons and other immune response mediators. This activation of the immune system helps in the defense against viral infections and enhances the antiviral response.

Storage

ConditionsStore in a cool and dry place.